John M. Cassara, Pharm.D Director of Pharmacy Services Foothill Presbyterian Hospital
PPI Information of PPI AND H2 Receptor Antagonists
Introduction: Current periodical literature as connotated possbile adverse reactions due to chronice,long-term use of PPis and H2 Receptor antagonists. The literature refers to possible C.Difficile outbreaks. malabsorption of calcium & Vitamin D. and increase of Community acquired pneumonia, and a possible increase of gastric cancer.
B. P&T Implications: The P&T Cotnrnittee shall review the above pexiodical literature and set-up possbile Drug Usage evaluations for patients who are admitted to the hospital for any of the above syndromes. The pharmacy department shnll review medication reconcilliatior for any of the above patients for drug-induced implications and report findings to the P&T for further appropriate action.
C. Pharmacy Depart:lllent Recommendations; For those patients admitted to FPH, only those patients needing antibiotics…Steriods, GI bleeds ,or emotional duress shall receive appropriate short-term PPI antagonist therapy. All other patients shall receive Maalox: AXIA-·3 as needed (PRN) therapy.
D.Outpatient Pharmacy/Physician Education! Copies 0£ the above studies reviewing shall be forwarded to our outpatient pharmacies end Medical Staff Physicians for their review,including pharmacy & P&T recommendations for the appropriate use of PPis and H2 Receptor antagonists for chronic treatment of hyperacidity.